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Verb tranquillise has 2 senses
calm, calm down, quiet, tranquilize, tranquillize, tranquillise, quieten, lull, still - make calm or still; "quiet the dragons of worry and fear"--1 is one way to comfort, soothe, console, solace
 Sample sentences:
 Somebody ----s somebody
 Something ----s somebody
 
sedate, calm, tranquilize, tranquillize, tranquillise - cause to be calm or quiet as by administering a sedative to; "The patient must be sedated before the operation"--2 is one way to affect
 Sample sentence:
 Somebody ----s somebody
 
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