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Adjective twofold has 2 senses
double, dual, twofold, treble, threefold - having more than one decidedly dissimilar aspects or qualities; "a double (or dual) role for an actor"; "the office of a clergyman is twofold; public preaching and private influence"- R.W.Emerson; "every episode has its double and treble meaning"-Frederick HarrisonAntonym:  single (indirect, via multiple)
 
double, doubled, twofold - twice as great or many; "ate a double portion"; "the dose is doubled"; "a twofold increase"Antonym:  single (indirect, via multiple)
 
 
Adverbial twofold has 1 sense
twofold, two times - by a factor of two; "the price increased twofold last year"
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