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Adjective puffy has 3 senses
bouffant, puffy - being puffed out; used of hair style or clothing; "a bouffant skirt"Antonyms:  small, little (indirect, via large, big)
 Antonyms:  small, little (indirect, via large, big)
 
bloated, distended, puffed, puffy, swollen, tumescent, tumid, turgid - abnormally distended especially by fluids or gas; "hungry children with bloated stomachs"; "he had a grossly distended stomach"; "eyes with puffed (or puffy) lids"; "swollen hands"; "tumescent tissue"; "puffy tumid flesh"Antonym:  healthy (indirect, via unhealthy)
 
huffing, puffing, puffy - breathing heavilyAntonyms:  breathless, dyspneic, dyspnoeic, dyspneal, dyspnoeal (indirect, via breathing)
 
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