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Adjective nescient has 2 senses
nescient, unbelieving - holding that only material phenomena can be known and knowledge of spiritual matters or ultimate causes is impossibleAntonym:  gnostic (indirect, via agnostic)
 
ignorant, nescient, unenlightened, unlearned, unlettered - lacking general education or knowledge; "an ignorant man"; "nescient of contemporary literature"; "an unlearned group incapable of understanding complex issues"; "exhibiting contempt for his unlettered companions"Antonym:  educated (indirect, via uneducated)
 
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