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Noun derangement has 2 senses
derangement, mental unsoundness, unbalance - a state of mental disturbance and disorientation--1 is a kind of insanity
 
upset, derangement, overthrow - the act of disturbing the mind or body; "his carelessness could have caused an ecological upset"; "she was unprepared for this sudden overthrow of their normal way of living"--2 is a kind of disturbance
 
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