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Definitions from the Web

Contrain

Part of Speech: Verb

Senses:

1. (Medical) To indicate or specify a medical condition or factor that makes a treatment or medication unsuitable.
2. (Technical) To restrict or limit the performance or effectiveness of something.
3. (Local) To refuse or decline an invitation or offer.

Usage:

Sense 1:

It is important for doctors to contraindicate certain medications to patients with existing allergies.

The contraindicated drug should be avoided in patients with heart disease.

Sense 2:

The overuse of antibiotics can lead to antibiotic resistance, contraindicating their effectiveness in treating some infections.

Heavy rain contraindicates playing outdoor sports in a grass field.

Sense 3:

Unfortunately, I must contrain attending the party due to previous commitments.

She contraindicated the job offer since it required long working hours.

Related Products:

• Medical Contraindications
• Technical Limitations
• Declining Invitations