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Verb act upon has 1 sense
influence, act upon, work - have and exert influence or effect; "The artist's work influenced the young painter"; "She worked on her friends to support the political candidate"--1 is one way to affect, impact, bear upon, bear on, touch on, touch
 Sample sentences:
 Somebody ----s something
 Somebody ----s somebody
 Something ----s somebody
 Something ----s something
 
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